16 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
F • 3 peaks: 1) ... Marrow (Toxic injury ... anemia Treatment ... oncology #hematology #diagnosis ... #management
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... #Differential # ... Diagnosis #Causes
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... normal - Infection (EBV ... transaminitis #differential ... #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... HBV, HCV, HEV, EBV ... #diagnosis #algorithm
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... renal injury, Strenuous ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... bearing after injury ... HSV, Varicella, EBV ... Reactive Syndrome - Acute
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... symptoms, or> 1 ... initiation • Differential ... organ dysfuxtion, ICU ... #management #hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... Diagnosis Framework ... Cord Causes: 1. ... Mycoplasma, Influenza, EBV ... Sensory level (1-
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Syndrome - Summary Acute ... Epidemiology: • 1- ... - HIV, CMV, EBV ... main variants: (1) ... #management #treatment
Radiation Injury
Acute Radiation Toxicity primarily affects rapidly dividing cells based on dosage
Hematopoiteic - Pancytopenia, Infection
 •
Acute Radiation ... people) = 4.5 Gy. 1 ... - MH/CCF/CWRU EM ... #Toxicity #diagnosis ... #management