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management disease rheumatology treatment adultonset agglutinin anemia causes cd4 ck classification cold creatine ebm elevated hemolytic hemophagocytic hlh hodgkins icl
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... the deadliest complication ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Coxsackie, CMV, EBV ... , Schnitzler) Complications ... Stills #Disease #diagnosis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... treatment #summary #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
CD4 Lymphopenia (ICL ... CRITERIA FOR ICL ... EBV. CMV. ... #Lymphopenia #ICL ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Mycoplasma, EBV ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology ... #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... - Lymphocyte rich ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... classification #hematology
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