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management oncology rheumatology treatment adultonset agglutinin anemia causes cd4 classification cold differential ebm hemolytic hemophagocytic hlh hodgkins icl idiopathic leukemia
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... the deadliest complication ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Coxsackie, CMV, EBV ... , Schnitzler) Complications ... #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... • Autoimmune diseases ... Adult-onset Still disease ... biologics (CMV +++, EBV ... of emergency, ICU
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... - Mycoplasma, EBV ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology ... #diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
CD4 Lymphopenia (ICL ... CRITERIA FOR ICL ... EBV. CMV. ... #Lymphopenia #ICL ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Cytopenia -> BM ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... - Lymphocyte rich ... lymph node biopsy (diagnostic ... number of sites of disease ... classification #hematology
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