10 results
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... to infection SEPTIC ... is a subset of sepsis ... Patients w/ septic ... of sepsis 2.
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Septic Arthritis ... beneficial in septic ... nongonococcal septic ... unable to rule out septic ... MetroHealth_EM #Septic
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 1999 - ICU ... - NEJM 2014 - Sepsis ... critically ill, septic ... /vmoitra) #EBM
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
- A Randomized Clinical ... admitted to the ICU ... #TTM48 #TTH48 #CriticalCare ... #ICU #VisualAbstract ... #EBM
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
• Giant cell arteritis ... Factitious fever • Trauma ... Tuleremia • Septic ... Infection: • HIV • EBV
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
endocarditis w/ septic ... Persistent fever, positive ... infection (e.g. septic ... arthritis, splenic ... Endocarditis #checklist #criticalcare
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
Sepsis - Interventions ... source - Have a sepsis ... has bacterial sepsis ... for persistent septic ... Factors #Matter #EBM
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... Coxsackie, CMV, EBV ... splenomegaly • Hepatic ... Disease #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Septal Hypertrophic Cardiomyopathy (HOCM)

52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) 
EM resident
Septal Hypertrophic ... Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... Cardiomyopathy #HOCM #HCM #clinical