9 results
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Tranexamic Acid (TXA ... Thinking MTP YES ICH ... Hemoptysis YES #TXA ... #Indications #management ... #EBM #trauma
CRASH-3: TXA for ICH? #TXA #managment #EBM #CRASH3 #trauma
CRASH-3: TXA for ... ICH? ... #TXA #managment ... #EBM #CRASH3 #trauma
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
TTP from other TMA ... admission to the ICU ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Coxsackie, CMV, EBV ... Visceral, DIC, TMA ... Disease #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... DIAGNOSTIC CRITERIA FOR ICL ... EBV. CMV. ... #Lymphopenia #ICL ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... - Lymphocyte rich ... physical exam, CT ... classification #hematology ... #oncology #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... dehydrogenase • Positive ... - Mycoplasma, EBV ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology