33 results
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Classification #Differential ... #Diagnosis #Nephrology
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Glomerulonephritis - Differential ... Strauss) Anti-GBM ... Glomerulonephritis #differential ... #diagnosis #nephrology
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
• Breaks in GBM ... Glomerular #Diseases #differential ... spectrum #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... #Proteinuria #Nephrology ... #Differential #
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Syndromes and Mimics - Differential ... Vasculitis - Anti-GBM ... Disease - Double Positive ... (ANCA + anti-GBM ... Syndromes #Mimics #Differential
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
GBM, Glomerular ... Kidney #Injury #Differential ... Causes #Sites #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Injury (AKI) - Differential ... disease, Anti-GBM ... Kidney #Injury #Differential ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Injury (AKI) - Differential ... GN: ANCA, Anti-GBM ... Kidney #Injury #Differential ... #Diagnosis #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... Renal #Syndrome #differential ... #diagnosis #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
of Hematuria - Differential ... exclude false positives ... nephropathy • Thin GBM ... ) • Anti-GBM ... #Hematuria #Differential