14 results
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Clinical construct ... was defined as positive ... likelihood of prolonged ICU ... recognition and treatment ... #criticalcare #icu
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 1999 - ICU ... - NEJM 2014 - Sepsis ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
Targeted Temperature Management ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Factors: • SICU ... > MICU, ♀, ↑Age ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... #Treatment #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: Infection (sepsis ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... Summary Clinical ... arthritis diagnosis Treatment ... patient admitted for treatment ... MH/CCF/CWRU EM
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
Sepsis - Interventions ... nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Coxsackie, CMV, EBV ... Disease #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Aplastic Anemia Clinical ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management