32 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
vs 24 Hours and Neurologic ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
POLAR Randomized Clinical ... Hypothermia on Neurologic ... did not improve neurologic ... #CriticalCare #ICU ... VisualAbstract #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... of emergency, ICU
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... - NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... : Influenza, EBV ... Rhabdomyolysis, Critical ... #Differential #Diagnosis ... #causes #neurology
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... host response to infection ... Clinical construct ... likelihood of prolonged ICU ... #criticalcare #icu
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... HSP • Post-infectious ... #Proteinuria #Nephrology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... #differential #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... Factors: • SICU ... > MICU, ♀, ↑Age ... : • Clinical Suspicion ... Management #Treatment #Hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
invasive fungal infection ... (IFI) in hematologic ... cut-offs defined in clinical ... - Frozen ice-pops ... Galactomannan #diagnosis