19 results
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
- Differential ... Diagnosis Framework ... Disease - Double Positive ... (ANCA + anti-GBM ... Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Renal Syndromes ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #Syndrome #differential ... #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Injury (AKI) - Differential ... Diagnosis Framework ... Abdominal Compartment Syndrome ... GN: ANCA, Anti-GBM ... #Diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Diagnosis Baseline ... ANCA, ANA, Anti-GBM ... Abdominal compartment syndrome ... syndrome: troponin ... #Diagnosis #nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
- Compatible syndrome ... granulomatosis: • EBV-associated ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
infections (HPV, EBV ... (Goodpasture's syndrome ... #Transplant #differential ... #diagnosis #kidney ... management #treatment #nephrology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... infarction, Acute renal ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Diagnosis Algorithm ... • Fanconi's syndrome ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... Coxsackie, HIV, CMV, EBV ... #Diagnosis #neurology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... antibody, Anti-GBM ... usually low in anti-GBM ... recent DAN) • EMG/NCS ... #Syndromes #differential