9 results
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Diagnosis Baseline ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM ... Anti-ds-DNA, C3/C4 ... #Diagnosis #nephrology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
- Differential ... Diagnosis Framework ... - Double Positive ... (ANCA + anti-GBM ... Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Renal Syndromes ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #Syndrome #differential ... #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Abdominal Compartment Syndrome ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... , C3/C4, Other ... #Diagnosis #nephrology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... infarction, Acute renal ... #differential # ... diagnosis #rhabdomyolysis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
DIAGNOSTIC ... chemotherapy) • Genetic syndromes ... EBV. CMV. ... #diagnosis #hematology ... #Differential #
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... Miller-Fisher GBS; Positive ... Rhombencephalitis #Differential ... #Diagnosis #Causes ... #Neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... pulmonary and renal ... Differential Diagnosis ... affects the skin, neurologic ... pain and GN Anti-GBM
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... dehydrogenase • Positive ... - Mycoplasma, EBV ... younger pts) Differential