20 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
investigations Risk ... yrs old; F>M Signs ... /Symptoms: - Fever ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Vasculitis
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Clinical Findings Risk ... Apolipoprotein E4 allele Risk ... chromosome 21) Signs ... #diagnosis #signs ... #symptoms
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
immunoglobulin reduces the risk ... Disease #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
PECARN Head CT Decision Aid

The Head CT Choice decision aid was developed in Rochester, Minnesota. Full
TBIs, the child’s risk ... observation, and signs ... and symptoms that ... PatientInfo #Peds #Pediatrics
Diseases of the Biliary Tract
Asymptomatic gallstones - Asymptomatic
Symptomatic gallstones - Biliary pain
Cholesterolosis of gallbladder - Usually
asymptomatic, high risk ... nausea, vomiting, fever ... , Murphy sign Chronic ... pain, jaundice, fever ... biliary #diseases #differential
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : Temperature rises ... Brucellosis Faget's Sign ... For every 1°F rise ... #Patterns #Differential
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
regardless of symptoms ... or signs. ... Cardiovascular risk ... AIDS #diagnosis #differential ... #signs #symptoms
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
hypotension develops • Risk ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
High-risk Features ... Ill-appearing, vital sign ... instability - New-onset fever ... Targetoid #Algorithm #Differential
Pediatrics Sepsis Screening
SIGNS OF INFECTION?
 • Fever (>38C)
 • Hypothermia (<36C)
 • Cough/chest pain/respiratory distress
 •
Screening SIGNS ... output • Other signs ... infection HIGH RISK ... • Other high-risk ... hospitalization SIGNS