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diagnosis management hematology differential mds myelodysplastic neurology nutrition alzheimersdisease apml ascorbicacid clinical dementia differentiation encephalopathy geriatrics hyponatremia myelodysplasia nephrology physicalexam
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... diagnosis and risk-stratification ... • Risks: infection ... #hematology #oncology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Clinical Findings Risk ... Apolipoprotein E4 allele Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
transfused patientsl • Risk ... without other cause ... : 33% • Treatment ... transfused patients • Risk ... hematology #diagnosis #comparison
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... Risk Factors: ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Caused commonly ... Pathophysiology: ... Risk factors: age ... Treatment: anticholinergics
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 Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Attempt if high risk ... management #hematology #oncology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia is usually caused ... Then, ask 3 questions ... the underlying cause ... puts patients at risk ... demyelination syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... Out Secondary Causes ... factor (GCSF) treatments ... and reducing the risk ... diagnosis #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Risk factors 3. ... the underlying cause ... • Treatment of ... with AEDs until cause
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Bone Groups at risk ... nonimmune hemolysis MSK ... , or any other cause ... vasculitis Treatment ... #AscorbicAcid #Pathophysiology
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