11 results
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Pathogenesis and Clinical ... activities reduced • Risky ... • Withdrawal symptoms ... #Pathophysiology ... Diagnosis #Signs #Symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Attempt if high risk ... Diagnosis: >3 symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Findings Risk ... Apolipoprotein E4 allele Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Alcohol Withdrawal Syndrome (AWS) - ICU OnePager

Scoring Alcohol Withdrawal Syndrome (AWS):
 • PAWSS
 • CIWA-Ar
 •
Withdrawal Symptom ... Minor Withdrawal Symptoms ... 3% - High risk ... diaphoresis) Treatment ... #management #etoh
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical ... Patients at Risk ... - History of alcohol ... Constipation - MSK ... #symptoms #signs
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... Risk Factors: ... History of excessive alcohol ... overload) Other Symptoms ... hyperparathyroidism Treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Bone Groups at risk ... , persons with alcohol ... poor nutrition Clinical ... nonimmune hemolysis MSK ... vasculitis Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... carries a variable risk ... arsenic compounds, alcohol ... factor (GCSF) treatments ... and reducing the risk
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
: Clinical Findings ... >2 days after EtOH ... Risk of having seizures ... #Pathophysiology ... #EtOH
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Risk factors 3. ... epilepticus Treatment ... underlying cause • Treatment