13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... (for secondary APS
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
- Differential Diagnosis ... Arthritis • Systemic Lupus ... Sicca) Syndrome ... Inflammatory #JointPain #MSK ... #Causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Motor Nerves: ALS ... heavy metals), Critical ... #differential #diagnosis
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Generalized fatigue - ALS ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia #Gravis #diagnosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... and treatment can ... Non-inflammatory causes ... MRI lesions and clinical ... consistent with MS
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... renal failure Clinical ... symptoms are not caused ... skin (16-32%): lupus ... anterior/posterior MSK
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Antibodies: Anti-Ro ... Antibodies: • Anti-Ro ... salivary ducts Clinical ... phenomenon (16%) MSK ... Adenocarcinoma Treatment
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
the follow up video ... fasciculus), which causes ... The most common causes ... the hospital, diagnosed ... with MS, and started
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... responsible for most cases ... Albuminuria, nephrotic syndrome ... ulcerated • MSK ... Syphilis #stages #diagnosis
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
(APLS) Testing ... - 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus ... #diagnosis #hematology