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diagnosis hematology algorithm causes anemia management cold eosinophilia naildisorders oncology palpable petechiae purpura rash systemic table agglutinin allergy atlas autoimmune
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Lymphoproliferative disorder ... , Autoimmune disorder ... Lymphoproliferative disorder ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Nail Disorders - Primary and Systemic Causes - Differential Diagnosis Algorithm #NailDisorders #Primary #Secondary #Systemic #dermatology #Differential
Nail Disorders - ... Systemic Causes - Differential ... NailDisorders #Primary #Secondary ... #Systemic #dermatology ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... #secondary
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... B12 deficiency, Orotic ... #Diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Hypersplenism • Secondary ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... Thrombocytopenia: ITP • Secondary ... DIC/TTP/HUS - Hemolytic ... #nonpalpable #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder ... Secondary Cold ... younger pts) Differential ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... • Starvation Secondary ... Lymphoproliferative Disorders ... Leukemia (CML) - Hemolytic ... High purine diet Secondary
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