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management differential infections infectiousdiseases reactions neurology product transfusion agglutinin alkaline alp anemia associated autoimmune causes coagulation cold comparison dementia dic
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... sensitivity of serum ... #AIDS #opportunistic ... InfectiousDiseases #Neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... deficiency • blood ... collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... : 2 hit mechanism ... to explain symptoms ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
originate from a low-grade ... Agglutinin Syndrome (CAS ... Mycoplasma, EBV, HIV ... sensitize red blood ... hemolytic #anemia #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Prolonged PT/PTT • Low ... protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
TRALI resembles ARDS ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
TRALI resembles ARDS ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusions #diagnosis ... #management #hematology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
(It's usually low ... Chest pain, cough, bloody ... Lymphadenopathy, CNS ... Constitutional symptoms ... #AIDS #pulmonary
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Major blood ... yeast • At risk: AIDS ... protein level • A low ... prep CSF and serum ... Aspergillosis Pathophysiology
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