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management reactions blood differential infections infectiousdiseases neurology product alkaline alp associated autoimmune causes coagulation comparison dementia dic disorder disseminated fungal
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: 2 hit mechanism ... to explain symptoms ... • Pathophysiology ... #Reactions #hematology ... #diagnosis #comparison
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... sensitivity of serum ... #AIDS #opportunistic ... InfectiousDiseases #Neurology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
TRALI resembles ARDS ... RBCs binds to serum ... Hypothermia: Due to low ... #diagnosis #management ... #hematology #reactions
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
RBCs binds to serum ... Hypothermia: Due to low ... Extremely rare - HIV ... #diagnosis #management ... #hematology #reactions
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Diuretics, PRBC transfusion ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum ... Hyophosphatasia #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Prolonged PT/PTT • Low ... protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... treatment #management #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
yeast • At risk: AIDS ... MC: CNS CSF: • ... protein level • A low ... prep CSF and serum ... Aspergillosis Pathophysiology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... or tenderness; serum ... or ALS • Very slow ... weakness + atrophy- Hip ... nucleotidase 1A (Anti cN
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