10 results
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Serum creatinine ... Angioneurotic edema ... failure - Co-medication ... active patients, Chronic ... contraindications #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
obtain the desired serum ... Side Effects: Edema ... patients sensitive to high ... medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... transfusion • HTN and edema ... Medications 2. ... causes #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... transfusion • HTN and edema ... Medications 2. ... causes #potassium #high ... #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Excretion #Diuresis #Nephrology ... #Pharmacology #Medications ... #Table
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... diuresis can be high ... : Hypovolemia, Hypervolemia ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... Treatments: • K-Binding ... caution in HTN & edema ... Treatment #potassium #nephrology
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl < 0.7, high ... after correcting serum ... Other medications ... #nephrology
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
, hypercalcemia, ... Overload (pulmonary edema ... chosen to match serum ... High clearance achieved ... RRT #managment #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
complements and a high ... lower extremity edema ... , and elevated serum ... with Lupus: • Chronic ... activation and/or medications