10 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... renal tubular acidosis ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... 4) Serum Uric Acid ... salt wasting By Rachel ... #nephrology #sodium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... acidosis: Gl tract ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Bartter syndrome, Gitelman ... the excretion of sodium ... urine #Algorithm #nephrology ... #differential # ... diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) ... ratio 0.5%) Differential ... Renal tubular acidosis ... #Syndrome #diagnosis ... #nephrology #management
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
(NAGMA) - Differential ... Diagnosis Framework ... #Metabolic #NAGMA ... #Differential ... #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... Diagnosis Algorithm ... - Bartter - Gitelman ... acidosis - Cl ... Pathophysiology #Nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Bartter syndrome, Gitelman ... acidosis: Proximal ... #Hypokalemia #diagnosis ... #Algorithm #differential ... #potassium #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Alkalosis: Differential ... Diagnosis ECF ... chronic respiratory acidosis ... furosemide-like lesion) • Gitelman ... #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Diagnosis Algorithm ... Release - Increased Serum ... Non-Anion Gap Metabolic ... Acidosis • Hyperosmolarity ... IntercellularShift #Nephrology