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dermatology erythematosus hematology management oncology signs sle symptoms vasculitis autoimmune behcet classification conditions disease extrarticular macrophage mas monoclonal myopathy myositis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #pain #skin #rashes ... #differential # ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... pain • Swan neck ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... lupus erythematosus ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Inflammation and pain ... of the joints ( ... - Lupus - Leukemia ... cutis Diagnosis ... Treatment: - Systemic
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... Scleroderma Thickened skin ... #pain #differential ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... vesicular eruption - Joints ... Diagnosis: Systemic ... lupus erythematosus ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... vesicular eruption • Joints ... tract: Abdominal pain ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Behcet disease) Differential ... Arthritis, AS Treatment ... Nonsurgical abdominal pain ... signs #symptoms #rheumatology
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