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Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... Sites of Action ... #Site #Action # ... Location #Nephrology ... Pathophysiology #Pharmacology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Acetazolamide, others SGLT2 ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... Thiazides-type diuretics ... #pharmacology # ... nephrology #medications ... #sites #action
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Pathophysiology - Diuretic ... Sites of Action ... Diuretics 1) ... #Sites #Action ... #nephrology #pharmacology
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of Diuretics ... #Diuretics # ... Sites #Action #Nephron ... #Pharmacology # ... Nephrology
#visualabstract #sglt2i #nephrology
#visualabstract ... #sglt2i #nephrology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... Action: Inhibits SGLT2 ... leading to osmotic diuresis ... EricsMedicalLectures/featured #SGLT2
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... are similar to diuretics ... /ambcarerx #SGLT2 ... #Inhibitors #Pharmacology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
a.k.a. osmotic diuresis ... : Conventional diuretics ... diabetes mellitus, SGLT2 ... Diagnosis #Causes #nephrology
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
ARNI, BBs, Loop diuretics ... , MRA, SGLT2i, Nitrate ... HFrEF #management #pharmacology