81 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... (SS), Polymyositis ... Kumfer @AnnKumfer #Antinuclear
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Comparison - Serotonin Syndrome ... Neuroleptic Malignant Syndrome ... #Serotonin #Syndrome ... Catatonia #NMS #SS ... diagnosis #management #treatment
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary Antinuclear ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment
Algorithm for the Diagnosis of Serotonin Syndrome
 - Serotonin syndrome is thought to be caused by
medication leading to SS ... - Clinical findings ... association with SS ... extremities in SS ... initiation of treatment
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... SLE), Sjogren's Syndrome ... (SS), Polymyositis ... Arthritis, Sjögren Syndrome
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 30-40% Target: SS-A ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... Lupusreference #Antinuclear
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's sign is a clinical ... Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... PhysicalExam #Video #Clinical ... #SJS #skin
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... Clinical Manifestations ... Treatment: • ... #SPS #Diagnosis ... #Management #treatment
Antibiotics for Intraabdominal Infection. 
Use your local antimicrobial susceptibility data for selecting the best empiric treatment!
the best empiric treatment ... the WSES/GAIS/SIS-E ... AAST 2021 global clinical ... #pharmacology #treatment
Treatment of NMS
 Dopamine antagonists should be discontinued immediately in patients suspected of NMS. Like SS,
Treatment of NMS ... Like SS, the mainstay ... treatment of NMS ... NeurolepticMalignant #Syndrome ... #NMS #Treatment