21 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... Patterns Nuclear ... Patterns: • Homogeneous ... pattern: - ... pattern: - SSc
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
- Nuclear Patterns ... Homogeneous pattern ... pattern: • SSc ... dots pattern: ... #Nuclear #Patterns
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... Antibodies #ANA #patterns
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Sjogren's Syndrome (SS ... scleroderma (SSc) • Nucleolar ... Antibodies #ANA #patterns
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... Cytoplasmic Patterns ... PBC/SSc OS, PBC/SjS ... Antinuclear #Antibody #Testing ... #Cytoplasmic #Patterns
Patterns of disease in advanced COPD

Type A: 
Pink Puffer (Emphysema Predominant) 
Major complaint is dyspnea, often
Patterns of disease ... usually pre- senting ... rare, with scant clear ... #COPD #Patterns
Flail Chest- Check out the paradoxical chest wall movement 
Typical management: opiates for analgesia, intubation due
movement Typical management ... Chest #Breathing #Pattern ... Video #Clinical #PhysicalExam
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
hepatocellular pattern ... though cholestatic pattern ... Autoantibodies: Auto-Nuclear ... Hepatitis (eg Viral) Management ... AIH #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Pathophysiology remains unclear ... Imaging Patterns ... DWI • White matter ... thrombosis Testing ... Syndrome #diagnosis #management
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
of the type and pattern ... #Diagnosis #Management ... #Differences #Algorithm