13 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... Nuclear Patterns ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Patterns Homogeneous ... pattern: • SLE ... ) Speckled pattern ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... Patterns Reticular ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Kumfer @AnnKumfer #Antinuclear ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... Antibodies #ANA #patterns
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... smear, HIV/HCV testing ... function test, ANA (e.g ... gastric bypass), LFT ... #Workup #hematology
Pulmonary Embolism on ECG 

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Triage EKG (no prior ... Differential/diagnosis ... See thread for POCUS ... (II, III, AVF)(pattern ... seen in 34% of cases
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... • Is there a pattern ... weeks) Can Be Caused ... an asymmetric pattern ... #Joint #pain #Differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Imaging Patterns ... Reversible course Differential ... thrombosis Testing ... the underlying cause ... with AEDs until cause
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... recent DAN) • EMG ... Goodpasture's cause ... • IF staining patterns ... Renal #Syndromes #differential