11 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... and Cytoplasmic Patterns ... Nuclear Patterns ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Testing - Nuclear Patterns ... Homogeneous pattern ... ) Speckled pattern ... #differential # ... diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Kumfer @AnnKumfer #Antinuclear ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... Testing Cytoplasmic Patterns ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Tests: • CBC • LFT ... - (C-ANCA) pattern ... - (P-ANCA) pattern ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... with a certain pattern ... #rheumatology
On the left a chest film of a 19 year old patient with Langerhans cell histiocytosis.
The
is a reticular patern ... recognized that this pattern ... was caused by multiple ... diagnosis in this ... #CXR #CTChest #
Pulmonary Embolism on ECG 

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Differential/diagnosis ... See thread for POCUS ... (II, III, AVF)(pattern ... seen in 34% of cases ... Electrocardiogram #clinical
Handlebar Traumatic Injury 
Young girl presents to you after low energy, helmeted bicycle accident. Her vitals
re-exams (normal CXR ... and/or delayed diagnosis ... Keep this injury pattern ... on your differential ... Trauma #Injury #clinical