110 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
D Discoid Rash ... Antinuclear Antibody (ANA ... Arthritis R Renal Disease ... IMDAMNSHARP #sle #systemic ... erythematosus #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Sjogren's Syndrome (SS ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... SSc: systemic sclerosis ... arthritis SLE : systemic ... #Differential #Comparison ... Table #Pulmonary #Rheumatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... : 2-8 weeks • Rash ... : 4-28 days • Rash ... #TEN #comparison ... #table #dermatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... arthritis, Skin rash ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Workup: - ANA ... Evolution: Chronic disease ... #Summary #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Disease! ... • Homogeneous: Systemic ... ) • Speckled: Systemic ... Sjogren's Syndrome (SS ... #patterns #rheumatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
and systemic toxicity ... assessed for Lyme disease ... pathognomonic for SJS ... systemic toxicity ... #Diagnosis #Dermatology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... gonorrhea, Rickettsial diseases ... Noninfectious: SJS ... SCVMCMed #Fever #Rash ... Differential #Diagnosis #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Petechial or purpuric rash ... of underlying disease ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology