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diagnosis differential lupus erythematosus management symptoms vasculitis anemia autoantibodies central chronic classification cll dermatology druginduced hemolytic leukemia lymphocytic macrophage maculopapular
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... • Immunologic Workup ... Evolution: Chronic disease ... Management #Summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... erythematosus [SLE ... Diagnosis #Management #Hematology ... #Rheumatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
Maculopapular Rashes - THE ALGORITHMIC ... assessed for Lyme disease ... rashes but without signs ... pathognomonic for SJS ... #Algorithm #Central
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... #Systemic #Lupus ... autoantibodies #signs ... #differential #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... Evolution: Chronic disease ... #comparison #table ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... vein thrombosis Hematologic ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... ): SS, SC, SE, Sβ ... , Hemoglobin H disease ... Differential #Diagnosis #Algorithm ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... , such as systemic ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... some time, let’s see ... #workup #hematology
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