7710 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus (SLE ... Erythematosus #SLE ... #MSK #Musculoskeletal
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Erythematosus (SLE ... Erythematosus #SLE
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Erythematosus (SLE ... Amy Chung, MD, MSc ... Joint #Disorders #msk
Shoulder Effusion Ballottement on Physical Examination

Shoulder effusion. You can ballot and see fluid return at posterior
can ballot and see ... #PhysicalExam #msk ... #orthopedics #clinical
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... is clinically suspected ... higly specific for SLE ... patients with typical SLE
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... phenomenon (16%) MSK
Demyelinating Diseases - Differential Diagnosis
 • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE
 •
Inflammatory: MS ... Polyarteritis nodosa, SLE
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Spondyloarthropathies, SLE ... retinal exudates) - SLE ... nodules - RA, SLE ... disease - RA - SLE ... • Seizures - SLE
Clarke's Test (Patellar Grind Test)

Indicates Patellofemoral dysfunction.
 - Patient with knee in extension. Push posterior on
of patella then ask ... Patellar #Grind #clinical ... Patellofemoral #msk
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... are evocative of SLE ... management of SLE