9 results
Selective Publication of Antidepressant Trials

A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... #Unpublished #Data ... #SSRIs #Evidence ... #Publication #Bias ... #Comparison #FDA
Selective Publication of Antidepressant Trials

A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... #Unpublished #Data ... #SSRIs #Evidence ... #Publication #Bias ... #Comparison #FDA
SNRls (Serotonin/Norepinephrine Reuptake Inhibitors) - FDA Approved Indications 

Venlafaxine (Effexor) - GAD, MDD, Panic Disorder, SAD
SNRls (Serotonin ... Inhibitors) - FDA ... commonly used antidepressants ... purpose of these medications ... #Psychiatry #FDA
Secondary causes of Hypertension
 • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Secondary causes ... Hypertension • Medications ... Pseudopheochromocytoma - respond to SSRIs ... Other Endocrine causes ... low renin HTN causes
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Buproprion, Tricyclic Antidepressants ... ucsdim #Serotonin #Syndrome ... #Pharmacology #medications ... #causes #differential
Shock - Differential Diagnosis by Classification
Reflex Syncope 
 - Vasovagal syncope
   • Prolonged standing
depletion - Medication ... e.g. αblockers, antidepressants ... Subclavian steal syndrome ... Alcohol blackout - Medication ... Classification #Table #Causes
Syncope - Differential Diagnosis Framework
Reflex Syncope:
• Vasovagal: Prolonged standing, Stress, Pain
• Situational: Coughing, Sneezing, Micturition, Defecation,
Volume Depletion • Medication ... Effect: a-blockers, antidepressants ... bradycardia, Sinus pauses ... Subclavian steal syndrome
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
to hours) after medication ... ingestion and most cases ... cessation of offending medication ... Agents: SSRls, SNRls ... TCAs, atypical antidepressants
Tenofovir is one of the most commonly used NRTI's! The original formulation is tenofovir disoproxil fumarate
the plasma to cause ... this is the only FDA ... approved medication ... review by the FDA ... enough clinical data