13 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... hyperglycemia in type 2 diabetes ... commonly used diabetes ... /ambcarerx #Diabetes ... #Drug #Endocrinology
Drugs causing hyperkalemia
 • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly
 •
Drugs causing hyperkalemia ... Cyclosporine, tacrolimus, Diabetes ... Drospirenone #Drugs ... #hyperkalemia # ... medications #causes
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
Antihypertensive Drugs ... (ACEI, ARB, diabetes ... failure - Co-medication ... Pgp-dependent drugs ... antihypertensive #medications
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... renal failure • Drugs ... • Diabetic Nephropathy ... • Type 1 #Hyperkalemia ... Diagnosis #algorithm #nephrology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes ... or neurogenic diabetes ... Idiopathic Nephrogenic diabetes ... or dipsogenic diabetes ... #Diabetes #Insipidus
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Ketoacidosis: Diabetic ... Drugs II. ... Hypokalemia ... Drug-induced hyperkalemia ... diagnosis #causes #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... reactions Common Drugs ... (Uncontrolled diabetes ... Medications 2. ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... reactions Common Drugs ... (Uncontrolled diabetes ... Medications 2. ... potassium #high #nephrology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Inhibitors Increasing Indications ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology ... #Euglycemic #Diabetic
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
artery stenosis • Drugs ... Proteinuria) • Diabetes ... eosinophiluria) • Drugs ... Hyperoxaluria • Hypercalcemia ... KidneyDisease #Nephrology