10 results
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Age-appropriate cancer ... screening (in absence ... - No other workup ... Age-appropriate cancer ... screening, CBC,
Cancer screening: Do the harms outweigh the benefits? #EBM #epidemioliogy #PubilcHealth #PrimaryCare #HONC #Screening #AdverseEffects #Harms
Cancer screening ... #EBM #epidemioliogy ... PrimaryCare #HONC #Screening ... FalsePositives #BMJ
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... BM Bx Consider ... • Nonmalignant hematologic ... Malignancy: Metastatic cancer
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... or if a primary hematologic ... When do you do a BM ... Diagnosis #Causes #Workup ... #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
in bone marrow (BM ... under 2%, then BM ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
helminthiasis, cancer ... - Myelogram/BM ... Diagnosis #Signs #Hematology ... #Workup
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... DIAGNOSIS Labs: • BMP ... antibody, Anti-GBM ... BNP, troponin if concern ... usually low in anti-GBM
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... from germinal center ... normal germinal center ... Hodgkin Lymphoma Workup ... classification #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... lymphoid organs When Cancer ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... acute HIV, HBV, EBV ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... differential #diagnosis #hematology