21 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Sjogren's Syndrome (SS ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Sickle Cell Crises Clinical ... Diagnosis #Management #Hematology ... Manifestations #Workup
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 30-40% Target: SS-A ... -15% If SLE is clinically ... Lupusreference #Antinuclear ... erythematosus #diagnosis #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
diverse genotypes): SS ... Diagnosis #Algorithm #workup ... #hematology #testing
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Sjogren's Syndrome (SS ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... autoantibodies (antinuclear ... management #phenotypes #workup ... #treatment #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... node biopsy • Clinical ... values supporting hematologic ... UnknownOrigin #workup
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
deficiency Work ... Measurement of antinuclear ... Algorithm #Causes #dermatology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
microbiological techniques Work-up ... antimicrobials, clinical ... - Assays for antinuclear ... #differential #workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... Management #Summary #rheumatology