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management antibiotics infant lp pediatrics stepbystep hemeonc oncology apml differentiation ebm emergencies evaluation hemophagocytic hlh leukostasis lymphohistiocytosis lysis oncologic perioperative
Validation of the Step-By-Step Approach to Febrile Infants #Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... #StepByStep #Algorithm ... #Antibiotics #Risk ... #Stratification ... #Fever #RebelEM
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #Febrile #Infant ... #Stratification
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... #Stratification ... #Fever
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... : - If febrile ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... Prednisone 5mg/kg ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... #management #hematology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... indicated • EKG ... Obtain EKG if: ... #Evaluation #stratification ... #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Fever + ANC ... work-up - If febrile ... ): - Hematologic ... mg/dL or > 25 % rise ... Oncology #HemeOnc #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... hyperinflammatory syndrome ... Fever b. ... Treatment Approach ... #Management #Hematology
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