12 results
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Manifestations of Monoclonal ... , Syndrome Schnitzler ... NaderYatim #monoclonal ... manifestations #dermatology ... #skin #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... capillary leak syndrome ... • Schnitzler syndrome ... #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... myopathy • Anti MAG ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... Cold Agglutinin Syndrome ... malignancy (CLL) - Monoclonal ... Viral Infection Clinical ... hemolytic #anemia #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... • Serotonin syndrome ... Anticholinergic syndrome ... Anesthesiology #Anesthesia #Checklist ... Diagnosis #Management #Workup
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
confirm reservoir bag ... using reservoir bag ... overload / TURP syndrome ... Intraoperative #Checklist ... Diagnosis #Management #Workup
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
an old house & works ... organ involvement, Ag ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Complications of Monoclonal ... Renal disease - Monoclonal ... glycoprotein (MAG ... rituximab (in clinical ... Complications #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... it represents a monoclonal ... Causes of Monoclonal ... endocrinopathy, monoclonal ... changes (POEMS syndrome