36 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Antibodies (MSAs) Dermatomyositis ... TIF1y, NXP2, Mi-2, SAE ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of dermatomyositis ... rash, 2) shawl sign ... Gottrons #Papules #Clinical ... #Photo
Thyroid Eye Signs 
Lid Signs
    Dalrymple’s Sign: Lid Retraction.
    Von
Thyroid Eye Signs ... : Lid lag of the ... Extra-Ocular Muscle ... intra-ocular pressure ... OPHTHALMOLOGY #clinical
Heliotrope Rash in Dermatomyositis

Peri-orbital edema and the heliotrope rash that we are all familiar with. Eyelid
Heliotrope Rash in Dermatomyositis ... flat, non scaly, macular ... Heliotrope #Rash #Dermatomyositis ... #Dermatology #Clinical ... #Photo #Face
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Purple #Urine #Bag ... pathophysiology #clinical ... #photo #differential
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... symptoms helps differentiate ... #Dermatology #Clinical ... #Photo #Neck
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... auricular papules Clinical ... #rheumatology #
Hutchinson's Sign
 - A sign of ophthalmic zoster
  - Multiple crusted vesicles in distribution of
Hutchinson's Sign ... - A sign of ophthalmic ... - High risk of ocular ... #Hutchinsons #Sign ... #clinical #photo
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... heliotrope, shawl sign ... Inflammatory #Myopathies #differential ... diagnosis #comparison #rheumatology
Holster Sign in Dermatomyositis

Interestingly, poikiloderma and violaceous erythema can occur in sun protected areas as well
Holster Sign in ... Dermatomyositis ... Thighs #SkinRash #Dermatomyositis ... #Dermatology #Clinical ... #Photo