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diagnosis algorithm abnormal aptt bruising coagulation management pt treatment anemia bilirubinemia cardiology chf classification clinical criticalcare disorders foamed heartfailure hemophilia
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential # ... hematology #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Rare • Drugs (e.g ... Coagulation #Bleeding ... #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... hematology #coagulation
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... 80-100 fL) • Bleeding ... Chronic Disease (e.g ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... epistaxis, gingival bleeding ... function test, ANA (e.g ... #Workup #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Sepsis • Drugs (e.g ... Dilatation on Ultrasound ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... disease) • aPTT is prolonged ... normal in mild cases ... hemophilia type (e.g ... Management #treatment #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Willebrand factor Ag ... the PT remains prolonged ... discern these causes ... #Diagnosis #Hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
importantly, bedside ultrasound ... ECG is vital while ... causing hypovolemia needing ... the determined cause ... #diagnosis #differential
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