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diagnosis dermatology rheumatology differential myositis oncology syndrome antimda5 antimda5dm antinxp2 antinxp2dm clinical common cutaneous distribution dm erythematosus lupus management manifestations
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... Autoimmune manifestations ... (dermatomyositis ... oncology #clinical #skin
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... Dermatomyositis ... can present with rash ... , Shaw sign, holster ... sign, and Gottron's
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... processes occur in the skin ... -> Heliotrope Rash ... flexors affected #Dermatomyositis ... Pathophysiology #Signs
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... multiforme - Dermatomyositis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Seizures • Strokes Skin
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... on sun-damaged skin ... macerated areas with satellite ... Acrochordons (skin ... #dermatology #rash
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... (blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign
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