6 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Cutaneous manifestations ... (blue-purple) rash ... • Erythematous rash ... anti-NXP2 Abs Lung Manifestations ... #rheumatology #dermatology
Manifestations of Anaphylaxis by Body System

Dermatologic/mucosal

 - Eyes: periorbital swelling/erythema, injected conjunctiva, tears

 - Oral mucosa:
Manifestations of ... Body System Dermatologic ... tongue and lips - Skin ... Diagnosis #Allergy #Signs ... #Symptoms #Anaphylaxis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... multiforme - Dermatomyositis ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... #rheumatology #dermatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... rash (Gottron papules ... and Gottron sign ... ) • Shawl sign ... Extramuscular manifestations