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diagnosis dermatology differential erythematosus lupus myositis sle symptoms vasculitis antimda5 antimda5dm antinxp2 antinxp2dm classification management myopathy oncology scleroderma sclerosis ssc
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... Dermatomyositis ... , Shaw sign, holster ... sign, and Gottron's ... Myositis #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... autoimmune disease ... thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... multiforme - Dermatomyositis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... diagnosis #management #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... central nervous system ... Presentation - Systemic ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... Presentation: Systemic ... purpura: Strong sign ... , mucositis • Rash ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system
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