29 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... scale - Holster sign ... #Diagnosis #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... infection • Lyme disease ... #differential #diagnosis ... #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... severity of the disease ... #rheumatology #
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... can present with rash ... , Shaw sign, holster ... sign, and Gottron's ... #rheumatology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... New-onset fever with rash ... sulfa-drug - Skin ... #Dermatology #Rash
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... the Nikolsky sign ... the Nikolsky sign ... includes Kawasaki disease ... fever or Nikolsky sign
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... -> Heliotrope Rash ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... hands & feet Signs ... - Generalized Skin ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology