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diagnosis dermatology differential rheumatology symptoms algorithm pathophysiology sle causes erythematosus petechiae systemic arthritis classification color common complications criteria ddxof dermatologic
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... lesions • Discoid lupus
SKIN RASHES Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
SKIN RASHES ... Skin rashes ... erythematous, maculopapular ... fever and systemic signs ... petechiae; #purpura; #rash
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... Suggestive of: Lupus ... Suggestive of: Lupus ... on texture of skin ... migrans: • Target sign
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Dermatology #Rash ... #Maculopapular
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... lesions (9.4%) • Maculopapular ... rash (6.7%) • ... Granulomatous vasculitis ... #dermatology #rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... Infection - Vasculitis ... - Autoimmune Vasculitis ... (lupus, RA, Sjogren's ... cryoglobulins • Skin
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... Seizures • Strokes Skin
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