13 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
lesions (9.4%) • Maculopapular ... rash (6.7%) • ... Differential Diagnosis ... #dermatology #rash ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... Sarcoidosis • GPA ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #differential #diagnosis
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - ... Diagnostic Algorithm ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Dermatology #Rash
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... (lupus, RA, Sjogren's ... , GPA, EGPA, Microscopic ... cryoglobulins • Skin ... Algorithm #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... - Differential Diagnosis ... migrans: • Target sign ... gabrieltalledop #dermatology ... #differential #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... , mucositis • Rash ... MPO > PR3 60/ GPA ... vesicles, pustules, maculopapular
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... ANCA-associated vasculitis ... Seizures • Strokes Skin ... Erythematosus #Diagnosis