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diagnosis differential pathophysiology rheumatology allergy anaphylaxis arteritis autoimmune classification complications dermatology disease extraarticular gca giantcell heat heatstroke illness kawasaki latent
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs ... #symptoms #complications
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
• Polymorphous rash ... hands & feet Signs ... - Generalized Skin ... Rash #Kawasaki ... #Symptoms #Vasculitis
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
Clinical manifestations ... (Skin and Mucosa ... #anaphylaxis #signs ... #symptoms #diagnosis ... #criteria #allergy
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Manifestations of ... tongue and lips - Skin ... : urticarial rash ... Diagnosis #Allergy #Signs ... #Symptoms #Anaphylaxis
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 Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... tract, and often causes ... mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... inflammation tends to cause ... pathophysiology #signs ... #symptoms #diagnosis
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... differential #diagnosis #causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms ... tract, and often causes
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... Leukocytoclastic vasculitis
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
Syphilis - Rash ... soles in 50% of cases ... exposure to or symptoms ... but do not meet criteria ... granuIomas on skin
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