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diagnosis dermatology oncology rheumatology syndrome antimda5 antimda5dm antinxp2 antinxp2dm clinical complications differential lupus management mucocutaneous myelodysplastic pathophysiology sle sweet symptoms
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... polymorphism • Satellite ... (dermatomyositis ... leukocytoclastic vasculitis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Cutaneous manifestations ... (blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... anti-NXP2 Abs Lung Manifestations
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... response -> Subacute cutaneous ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Most common extra cutaneous ... Episcleritis Signs ... multiforme - Dermatomyositis ... Leukocytoclastic vasculitis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... (blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign
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