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diagnosis rheumatology dermatology symptoms differential pathophysiology syndrome dermatomyositis lupus management oncology peds sle antimda5 antimda5dm antinxp2 antinxp2dm autoimmune behcet classification
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... appearing during the disease ... polymorphism • Satellite ... leukocytoclastic vasculitis ... oncology #clinical #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... • Pauci-immune vasculitis ... Maculopapular rash ... Granulomatous vasculitis ... #dermatology #rash
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
Suggestive clinical manifestations ... - Clinical manifestations ... - Systemic disease ... , skin-dominant ... Rheumatology #Peds #Pediatrics
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... - Skin, glomeruli ... mucositis - Rash ... purpura: strong sign
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... purpura: Strong sign ... , mucositis • Rash ... cmpkx deposits skin ... : • Skin lesions
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... M > F Clinical Manifestations ... response to local skin ... test (this is a skin ... diagnosis #management #signs
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... of skin (esp. over ... blood vessels (vasculitis ... interstitial lung disease ... pathophysiology #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... pain (20%) Renal disease ... erythematosus #signs
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous manifestations ... (blue-purple) rash ... • Erythematous rash ... severity of the disease ... anti-NXP2 Abs Lung Manifestations
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