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diagnosis symptoms rheumatology differential lupus sle classification complications criteria dermatology dermatomyositis dm erythematosus extraarticular kawasaki manifestations mucocutaneous oncology peds pm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... - Skin, glomeruli ... mucositis - Rash ... purpura: strong sign
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... • Polymorphous rash ... - Generalized Skin ... #Diagnosis #Pathophysiology ... #Vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... purpura: Strong sign ... , mucositis • Rash ... cmpkx deposits skin ... : • Skin lesions
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... pain (20%) Renal disease ... erythematosus #signs
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... blood vessels (vasculitis ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... -> Heliotrope Rash ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... Leukocytoclastic vasculitis
Pediatrics Sepsis Screening SIGNS OF INFECTION? • Fever (>38C) • Hypothermia (<36C) • Cough/chest pain/respiratory distress •
Pediatrics Sepsis ... vomiting/diarrhea • Skin ... pain/swelling/rash ... neuromuscular disease ... <94%, mottled skin
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