13 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... • Arthralgia/arthritis ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... • Gonococcal arthritis ... • Psoriatic arthritis ... differential #diagnosis #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... heliotrope rash, Shaw sign ... , holster sign, ... myositis, and arthritis ... Myositis #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... diagnosis #management #signs ... #symptoms #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
of the joints (arthritis ... Episcleritis Signs ... of the joints (arthritis ... multiforme - Dermatomyositis ... Neutrophilic rheumatoid arthritis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... of hip (rare), Arthritis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... systemic sx + signs ... required due to skip ... them, but urgent rheumatology ... GCA #Temporal #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... purpura: strong sign ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... GCA (Giant Cell Arteritis ... mucositis • Rash, arthritis ... and often causes arthritis ... Differential #Diagnosis #Rheumatology