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diagnosis differential management erythematosus lupus myositis syndrome systemic vasculitis ana antibodies antinuclear arteritis behcet classification disease gca giantcell joint monoarthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... Rheumatologic Disease ... • SLE • Psoriatic ... Symmetrical: • RA • SLE
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs ... #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... myositis, and arthritis ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... like rheumatoid arthritis ... erythematosus (SLE ... ) Signs / Symptoms ... Xeroderma (Dry skin
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... : SLE, Reactive ... Nonsurgical abdominal pain ... diagnosis #management #signs ... #symptoms #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Positive ANA ≠ Autoimmune ... context of other symptoms ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... disease • Non-autoimmune ... rheumatologic diseases ... : • Joint pain ... Induced Lupus: • Symptoms
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... claudication: pain ... chews, not just pain ... required due to skip ... them, but urgent rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Presentation - Systemic Symptoms ... purpura: strong sign ... , testes -> pain ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
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