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diagnosis differential symptoms dermatology erythematosus systemic classification complications hematology joint management pain syndrome aortitis arthritides arthritis behcet conditions cryoglobulinemia cryoglobulins
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Thrombosis and arterial ... such as systemic lupus ... purpura: strong sign ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Erythematosus #SLE ... Complications #pathophysiology ... #signs #symptoms
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ANCA associated vasculitis ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
Arthritis: Viral, Bacterial ... Disease: Systemic Lupus ... Erythematous, Systemic Vasculitis ... Undifferentiated UCSD ... Differential #Diagnosis #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PALPABLE PURPURA: Vasculitis ... Leukocytoclastic vasculitis ... • Ig A vasculitis ... associated small vessel vasculitis ... HCV, HBV Not Vasculitis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Mechanisms (Principally Vasculitis ... • IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... #vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... syndrome • Coronary arteries ... Thrombosis and arterial ... Differential #Diagnosis #Rheumatology
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