9 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... manifestations - Skin ... with purpura - Renal ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... vasculitis Associated ... • Absence of skin ... #Vasculitis #Management ... #Rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... - 10% SLE or RA ... - 5 to 20% Sjögren's ... reticularis & skin ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... Vasculitis - Skin ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(15%) Skin (85% ... Butterfly rash, Vasculitis ... Abdominal pain (20%) Renal ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA ... Distal (Type I) renal ... : • 7%, Cryoglobulinemia ... #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... pulmonary and renal ... purpura: Strong sign ... / ANCA + MPO) Cryoglobulinemic ... Differential #Diagnosis #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Complications of DMARDs • Skin ... Vascular: Rheumatoid vasculitis ... Pericarditis • Renal ... Rheumatoid #Arthritis #RA ... #diagnosis #rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
• Inner ear • Skin ... Most common • Sjogren ... Heart failure • Renal ... Polychondritis #rheumatology ... #diagnosis #management